Heike, Keilhack: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Sensitive multiplexed analysis of kinase activities and activity-based kinase identification

Nagashima, Kumiko, Krauss, Stefan, Paweletz, Cloud, Kubota, Kazuishi, Anjum, Rana, Yu, Yonghao, Kunz, Ryan C, Andersen, Jannik N, Kraus, Manfred, Keilhack, Heike

Journal:

Nature Biotechnology

Year:

2009

Language:

english

File:

PDF, 823 KB

english, 2009

2

Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations

M. Golam Mohi, Ifor R. Williams, Charles R. Dearolf, Gordon Chan, Jeffery L. Kutok, Sarah Cohen, Kelly Morgan, Christina Boulton, Hirokazu Shigematsu, Heike Keilhack, Koichi Akashi, D. Gary Gilliland,

Journal:

Year:

2005

Language:

english

File:

PDF, 923 KB

english, 2005

3

Comparative expression analysis of four breast cancer subtypes versus matched normal tissue from the same patients

Paolo G.V. Martini, Deanne M. Taylor, Jadwiga Bienkowska, Jennifer Jackson, Gregory McAllister, Heike Keilhack, Robert K. Campbell

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 292 KB

english, 2008

4

A687V EZH2 is a gain-of-function mutation found in lymphoma patients

Christina R. Majer, Lei Jin, Margaret Porter Scott, Sarah K. Knutson, Kevin W. Kuntz, Heike Keilhack, Jesse J. Smith, Mikel P. Moyer, Victoria M. Richon, Robert A. Copeland, Tim J. Wigle

Journal:

Year:

2012

Language:

english

File:

PDF, 448 KB

english, 2012

5

Evidence of mTOR Activation by an AKT-Independent Mechanism Provides Support for the Combined Treatment of PTEN-Deficient Prostate Tumors with mTOR and AKT Inhibitors

Zhang, Weisheng, Haines, Brian B., Efferson, Clay, Zhu, Joe, Ware, Chris, Kunii, Kaiko, Tammam, Jennifer, Angagaw, Minilik, Hinton, Marlene C., Keilhack, Heike, Paweletz, Cloud P., Zhang, Theresa, Win

Journal:

Translational Oncology

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

6

Negative Regulation of Ros Receptor Tyrosine Kinase Signaling: An Epithelial Function of the SH2 Domain Protein Tyrosine Phosphatase SHP-1

Heike Keilhack, Marit Müller, Sylvia-Annette Böhmer, Carsten Frank, K. Michael Weidner, Walter Birchmeier, Tanja Ligensa, Alexander Berndt, Hartwig Kosmehl, Bernd Günther, Thomas Müller, Carmen Birchm

Journal:

The Journal of Cell Biology

Year:

2001

Language:

english

File:

PDF, 3.61 MB

english, 2001

7

Binding of Phosphatidic Acid to the Protein-Tyrosine Phosphatase SHP-1 as a Basis for Activity Modulation †

Frank, Carsten, Keilhack, Heike, Opitz, Frank, Zschörnig, Olaf, Böhmer, Frank-D.

Journal:

Year:

1999

Language:

english

File:

PDF, 136 KB

english, 1999

8

Durable Tumor Regression in Genetically Altered Malignant Rhabdoid Tumors by Inhibition of EZH2

Heike, Keilhack

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 58 KB

english, 2014

9

Reaction Coupling between Wild-Type and Disease-Associated Mutant EZH2

Swalm, Brooke M., Knutson, Sarah K., Warholic, Natalie M., Jin, Lei, Kuntz, Kevin W., Keilhack, Heike, Smith, Jesse J., Pollock, Roy M., Moyer, Mikel P., Scott, Margaret Porter, Copeland, Robert A., W

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.42 MB

english, 2014

10

EPZ011989, A Potent, Orally-Available EZH2 Inhibitor with Robust in Vivo Activity

Campbell, John E., Kuntz, Kevin W., Knutson, Sarah K., Warholic, Natalie M., Keilhack, Heike, Wigle, Tim J., Raimondi, Alejandra, Klaus, Christine R., Rioux, Nathalie, Yokoi, Akira, Kawano, Satoshi, M

Journal:

ACS Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.45 MB

english, 2015

11

Small molecule inhibitors of EZH2: the emerging translational landscape

Keilhack, Heike, Smith, Jesse J

Journal:

Year:

2015

Language:

english

File:

PDF, 1.15 MB

english, 2015

12

The importance of being Me: Magic methyls, methyltransferase inhibitors and the discovery of tazemetostat.

Kuntz, Kevin W, Campbell, John Emmerson, Keilhack, Heike, Pollock, Roy M, Knutson, Sarah K, Porter Scott, Margaret, Richon, Victoria M, Sneeringer, Chris J, Wigle, Tim J, Allain, Christina J, Majer, C

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 468 KB

english, 2016

13

PRC2 and SWI/SNF Chromatin Remodeling Complexes in Health and Disease

Kadoch, Cigall, Copeland, Robert A., Keilhack, Heike

Journal:

Year:

2016

Language:

english

File:

PDF, 2.47 MB

english, 2016

14

Initial testing (stage 1) of tazemetostat (EPZ-6438), a novel EZH2 inhibitor, by the Pediatric Preclinical Testing Program

Kurmasheva, Raushan T., Sammons, Melissa, Favours, Edward, Wu, Jianwrong, Kurmashev, Dias, Cosmopoulos, Katherine, Keilhack, Heike, Klaus, Christine R., Houghton, Peter J., Smith, Malcolm A.

Journal:

Pediatric Blood & Cancer

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

15

Regulation of Brown Fat Adipogenesis by Protein Tyrosine Phosphatase 1B

Matsuo, Kosuke, Bettaieb, Ahmed, Nagata, Naoto, Matsuo, Izumi, Keilhack, Heike, Haj, Fawaz G., Orsulic, Sandra

Journal:

Year:

2011

Language:

english

File:

PDF, 989 KB

english, 2011

16

Enabling Drug Discovery for the PARP Protein Family through the Detection of Mono-ADP-Ribosylation

Lu, Alvin Z., Abo, Ryan, Ren, Yue, Gui, Bin, Mo, Jan-Rung, Blackwell, Danielle, Wigle, Tim, Keilhack, Heike, Niepel, Mario

Journal:

Biochemical Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.35 MB

english, 2019